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Thienodiazepine overdose may perhaps arise when a thienodiazepine is taken in very hefty portions or concurrently with other depressants. This is especially perilous with other GABAergic depressants for instance barbiturates and Liquor due to the fact they do the job in an identical style, but bind to distinct allosteric sites within the GABAA receptor, Therefore their effects potentiate one another.

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